Liga Zvejniece Selected Research

3-(2,2,2-trimethylhydrazine)propionate

9/2011	Mildronate treatment improves functional recovery following middle cerebral artery occlusion in rats.
9/2010	Mildronate exerts acute anticonvulsant and antihypnotic effects.
8/2009	Protective effects of mildronate in an experimental model of type 2 diabetes in Goto-Kakizaki rats.

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Liga Zvejniece Research Topics

Disease

5	Seizures (Absence Seizure) 01/2023 - 09/2010
4	Encephalitis (Encephalitis, Rasmussen) 04/2010 - 12/2005
3	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 12/2023 - 09/2011
3	Hypoxia (Hypoxemia) 12/2023 - 01/2020
3	Necrosis 10/2020 - 08/2009
3	Pain (Aches) 08/2009 - 10/2006
3	Inflammation (Inflammations) 12/2007 - 12/2005
2	Neuroinflammatory Diseases 01/2024 - 01/2004
2	Infarction (Infarctions) 12/2023 - 09/2011
2	Traumatic Brain Injuries (Traumatic Brain Injury) 10/2021 - 01/2020
2	Body Weight (Weight, Body) 01/2017 - 12/2007
2	Brain Ischemia (Cerebral Ischemia) 11/2016 - 09/2011
1	Liver Failure 04/2024
1	Post-Acute COVID-19 Syndrome 01/2024
1	Fatigue 01/2024
1	Reperfusion Injury 12/2023
1	Ischemia 12/2023
1	Autism Spectrum Disorder 01/2023
1	Brain Diseases (Brain Disorder) 01/2023
1	Epilepsy (Aura) 01/2023
1	Reflex Epilepsy (Photosensitive Epilepsy) 01/2023
1	Anhedonia 07/2022
1	Mental Disorders (Mental Disorder) 07/2022
1	Adenocarcinoma 01/2022
1	Neurodegenerative Diseases (Neurodegenerative Disease) 10/2021
1	Substance-Related Disorders (Drug Abuse) 09/2020
1	Sleepiness 09/2020
1	Schizophrenia (Dementia Praecox) 12/2019
1	Cognitive Dysfunction 10/2019
1	Nervous System Diseases (Neurological Disorders) 01/2017
1	Obesity 01/2017
1	Weight Gain 01/2017
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2017
1	Hyperglycemia 01/2017
1	Stroke (Strokes) 11/2016
1	Hyperalgesia 10/2015
1	Neuralgia (Stump Neuralgia) 10/2015
1	Type 2 Diabetes Mellitus (MODY) 08/2009
1	Coronary Occlusion 08/2009
1	Diabetes Complications 08/2009

Drug/Important Bio-Agent (IBA)

5	4-amino-3-phenylbutyric acid (phenibut)IBA 09/2020 - 03/2008
4	Sigma-1 ReceptorIBA 01/2023 - 01/2017
4	MelanocortinsIBA 10/2006 - 01/2004
3	Glucose (Dextrose)FDA LinkGeneric 04/2024 - 08/2009
3	LigandsIBA 01/2023 - 01/2017
3	Proteins (Proteins, Gene)FDA Link 01/2022 - 01/2017
3	3-(2,2,2-trimethylhydrazine)propionateIBA 09/2011 - 08/2009
3	Nitric Oxide (Nitrogen Monoxide)FDA Link 04/2010 - 06/2006
3	Melanocortin Receptors (Melanocortin Receptor)IBA 12/2007 - 12/2005
3	Peptides (Polypeptides)IBA 10/2006 - 01/2004
2	Fatty Acids (Saturated Fatty Acids)IBA 04/2024 - 08/2009
2	Carnitine (L-Carnitine)FDA LinkGeneric 01/2023 - 08/2009
2	Neuroprotective AgentsIBA 10/2021 - 11/2016
2	Pentylenetetrazole (Metrazol)IBA 01/2021 - 10/2015
2	imidazole mustard (BIC)IBA 01/2021 - 01/2017
2	Interleukin-1beta (Interleukin 1 beta)IBA 10/2020 - 04/2010
2	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 10/2020 - 04/2010
2	Dizocilpine Maleate (Dizocilpine)IBA 12/2019 - 10/2019
2	Blood Glucose (Blood Sugar)IBA 01/2017 - 08/2009
2	LipopolysaccharidesIBA 04/2010 - 12/2007
2	NF-kappa B (NF-kB)IBA 04/2010 - 12/2005
2	beta-MSHIBA 10/2006 - 12/2005
1	Acetylcarnitine (Alcar)IBA 01/2024
1	methyl-gamma-butyrobetaineIBA 12/2023
1	Reactive Oxygen Species (Oxygen Radicals)IBA 12/2023
1	triphenyltetrazoliumIBA 12/2023
1	acylcarnitineIBA 12/2023
1	trimethyl-lysine hydroxylaseIBA 01/2023
1	Sucrose (Saccharose)IBA 07/2022
1	BicucullineIBA 01/2021
1	GABA-B ReceptorsIBA 01/2021
1	Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone (FCCP)IBA 11/2020
1	Glutamic Acid (Glutamate)FDA Link 11/2020
1	CalciumIBA 01/2020
1	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 12/2019
1	LeptinIBA 01/2017
1	Appetite Depressants (Anorectics)IBA 01/2017
1	N,N- dipropyl- 2- (4- methoxy- 3- (2- phenylethoxy)phenyl)ethylamine monohydrochlorideIBA 01/2017
1	2- (4- morpholino)ethyl- 1- phenylcyclohexane- 1- carboxylateIBA 01/2017
1	S-phenylpiracetamIBA 01/2017
1	1- (3,4- dimethoxy- 2- - chlorobenzylideneamino)guanidineIBA 04/2010
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 04/2010
1	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 04/2010
1	Phenylephrine (Neo-Synephrine)FDA LinkGeneric 08/2009
1	FructosamineIBA 08/2009
1	CarbohydratesIBA 08/2009
1	Antidepressive Agents (Antidepressants)IBA 03/2008
1	Type 4 Melanocortin Receptor (Melanocortin-4 Receptor)IBA 12/2007
1	melanotan-IIIBA 12/2007
1	Formaldehyde (Formol)FDA Link 10/2006
1	Analgesics (Analgesic Drugs)IBA 10/2006
1	alpha-MSHIBA 10/2006
1	gamma-MSHIBA 10/2006
1	Indomethacin (Indometacin)FDA LinkGeneric 10/2006
1	Melanocyte-Stimulating Hormones (MSH)IBA 10/2006
1	Hormones (Hormone)IBA 10/2006
1	Type 3 Melanocortin ReceptorIBA 06/2006

Therapy/Procedure

1	Therapeutics 01/2023